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Drug Interactions

[1], interactions involving OTC drugs can produce unwanted results or make medicines less effective. It's especially important to know about drug interactions [2].
Some drugs can also interact with foods and beverages, as well as with health conditions such as diabetes, kidney disease, and high blood pressure.
Here are a few drug interaction cautions for some common OTC ingredients:

  • Avoid alcohol if you are taking antihistamines, cough-cold products with the ingredient dextromethorphan, or drugs that treat sleeplessness.
  • Do not use drugs that treat sleeplessness [3].
  • Check with your doctor before taking products containing aspirin if you're taking a prescription blood thinner or if you have diabetes or gout.
  • [4] when you have stomach pain, nausea, or vomiting.
  • [5], do not use a nasal decongestant if you are taking a prescription drug for high blood pressure or depression, or if you have heart or thyroid disease, diabetes, or prostate problems.

Do not use laxatives if you're taking Rx and OTC drugs at the same time
Unless directed by a doctor Drug interactions may make your drug less effective
Although mild and relatively uncommon if you are taking prescription sedatives or tranquilizers